To explore the significance of serum osteocalcin levels in hemodialysis patients in the diagnosis of high transport bone disease. Methods Collect 62 patients (mean age 55.42 ± 14.67 years) general clinical data of maintenance hemodialysis patients, determine serum calcium (Ca), phosphorus (P), calcium and phosphorus product (Ca × P), alkaline phosphatase (ALP), The whole segment of parathyroid hormone (iPTH) and osteocalcin (BGP). Using iPTH> 450 ng / L as standard one (group A), iPTH> 450 ng / L and BGP> 8 μg / L as standard two (group B), respectively, predict high transport bone disease. Results There was no significant difference in serum Ca, P, Ca × P and ALP between the two groups. Standard 1 predicts that patients with high-transport bone disease account for 50.7% of the included cases, of which BGP <1.5 μg / L accounts for 33%. Criterion 2 predicts that high transport bone disease accounts for 38.5% of the included cases. Conclusion Serum BGP and iPTH levels in hemodialysis patients are significantly increased (P> 0.01, P> 0.01). The simultaneous use of serum BGP and iPTH to predict high transport bone disease has very important clinical significance.
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