The major scientific research project undertaken by the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences, "Research on New Technologies and New Methods for Protein Separation and Identification" passed the acceptance of the subject in Dalian. The chief scientist of the project, Academician Zhang Yukui, served as the acceptance team leader, Academician Yao Shouzhuo, Hunan University, Researcher Yao Zhijian, National Human Genome North Research Center, Researcher Liu Maili, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Professor Jiang Yunbao, Xiamen University, Professor Guo Lin, Wuhan University, etc. Member of the expert group. Relevant leaders from the Basic Bureau of the Chinese Academy of Sciences and the Basic Department of the Ministry of Science and Technology attended the acceptance meeting.
The expert group of the project acceptance meeting listened to the four project leaders on the research content and goals, the completion of the research tasks, the level and innovation of the research results, the contribution to the overall goal of the project, the research team and talent training, and data sharing and technical data archiving The situation and other aspects of the report, reviewed the summary of the acceptance of various topics. After careful discussion, the expert group fully affirmed the research work of each topic, and agreed that each task group carried out work in strict accordance with the research content in the planned task book, and developed high-throughput high-abundance protein removal and low-abundance protein enrichment. Methods and materials, developed a variety of protein efficient separation technology platforms with independent intellectual property rights and high sensitivity identification new technology and new methods for liquid chromatography-mass spectrometry, and high-abundance protein removal in plasma proteins, protein post-translational modification, peptidomics and The screening of potential disease-related proteins has been applied, providing important technical support for the research of discovering proteins with important biological functions, clarifying the mechanism of disease occurrence, screening disease-related biomarkers, and searching for drug targets. In order to complete the scheduled research tasks, the average score of each subject is excellent.
During the implementation of the project, 258 SCI papers were published and 63 patents were applied for, including 3 software copyrights, 13 Chinese authorized patents, and 1 US authorized patent; 1 published monograph and 3 translated books.
At the same time, the expert group also put forward pertinent opinions and suggestions on the implementation of the subject and the next development plan.
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